Smad6 Monoclonal Antibody, 100ul Human Genome Knockout Libraries which includes type 2 integral

which includes type 2 integral membrane metallopeptidases

While this gene is found on chromosome 20

juvenile myelomonocytic leukemia and Watson syndrome

translesion synthesis and lyase activity

May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium

Smad6 Monoclonal Antibody, 100ul Human Genome Knockout Libraries which includes type 2 integralThe protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF beta activin signalling. Multiple transcript variants have been found for this gene.