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IRF3 Polyclonal Antibody, 50ul Cell Senescence This protein may be the

SKU: 34962655482

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IRF3 Polyclonal Antibody, 50ul Cell Senescence This protein may be theIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed

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Description

This protein may be the target of oncogenic mutations in breast or ovarian cancer

HNRNPCL1 (Heterogeneous Nuclear Ribonucleoprotein C-Like 1) is a Protein Coding gene

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12

The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses

Contains 1 CRIB domain

IRF3 Polyclonal Antibody, 50ul Cell Senescence This protein may be theIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed

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