Human Adam Dec1, ADAMDEC1 ELISA Kit, 96T Syringe Filter The N-terminal region is required

The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity

The encoded protein may play a role in endocytic trafficking

Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins

This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family

F-box proteins are divided into three classes depending on the interaction substrate domain each contains in addition to the F-box motif: FBXW proteins contain WD-40 domains| FBXL proteins contain leucine-rich repeats| and FBXO proteins contain either different protein-protein interaction modules or no recognizable motifs

Human Adam Dec1, ADAMDEC1 ELISA Kit, 96T Syringe Filter The N-terminal region is required