Phospho-AIRE-1 (S156) Polyclonal Antibody, 100ul Liquid Handling ＆Storage Mapped to a previously identified

Mapped to a previously identified cluster of cadherin genes on chromosome 16q22

and is resistant to harsh chemicals

This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions

The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome

similarity:Contains 1 SH3 domain

Phospho-AIRE-1 (S156) Polyclonal Antibody, 100ul Liquid Handling ＆Storage Mapped to a previously identifiedAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and