Mouse Group Xiia Secretory Phospholipase A2, PLA2G12A ELISA Kit, 96T Miscellaneous RAD17 checkpoint clamp loader component

RAD17 checkpoint clamp loader component binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage

enzyme regulation:Two specific sites

Cofilin 1 encoded by CFL1 can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner

They are involved in a variety of biological processes

Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described

Mouse Group Xiia Secretory Phospholipase A2, PLA2G12A ELISA Kit, 96T Miscellaneous RAD17 checkpoint clamp loader componentPA2 catalyzes the calcium dependent hydrolysis of the 2 acyl groups in 3 sn phosphoglycerides. Does not exhibit detectable activity toward sn 2 arachidonoyl or linoleoyl phosphatidylcholine or phosphatidylethanolamine (By similarity).