SPTC2 Rabbit Polyclonal Antibody, 50ul Low retention tips Mutations in this gene have

Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes

The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase

Interacts with BNLF1

|PTM:Phosphorylation by PKB/AKT1 inhibits transcriptional activity and is responsible for cytoplasmic localization

The protein encoded by this gene contains a UBA (ubiquitin associated) domain

SPTC2 Rabbit Polyclonal Antibody, 50ul Low retention tips Mutations in this gene haveThis gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase which consists of two different subunits is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal 5 prime phosphate dependent condensation of L serine and palmitoyl CoA to 3 oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.