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HRI Polyclonal Antibody, 50ul DNA Oligo Synthesis API5 encodes an apoptosis inhibitory

SKU: 35442440001

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HRI Polyclonal Antibody, 50ul DNA Oligo Synthesis API5 encodes an apoptosis inhibitoryEukaryotic translation initiation factor 2 alpha kinase 1encoded by EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

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Description

API5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation

Mutations in this gene have been associated with left-right axis malformations| particularly in the heart and lungs

Belongs to the CYFIP family

the protein binds to iron-responsive elements (IREs)

FEV is fused to the Ewing sarcoma (EWS) gene following chromosome translocations

HRI Polyclonal Antibody, 50ul DNA Oligo Synthesis API5 encodes an apoptosis inhibitoryEukaryotic translation initiation factor 2 alpha kinase 1encoded by EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

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