Human Histone H2A Type 2-C, HIST2H2AC ELISA Kit, 96T Sealing Film CCNC and CDK8 subunits form

CCNC and CDK8 subunits form a distinct module termed the CDK8 module

Keratin 20 encoded by KRT20 is a member of the keratin family

inhibits their kinase activity

Its striking orange color adds a touch of boldness to your lab experiments

It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters

Human Histone H2A Type 2-C, HIST2H2AC ELISA Kit, 96T Sealing Film CCNC and CDK8 subunits formCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones, also called histone code, and nucleosome remodeling.