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LRC3B Rabbit Polyclonal Antibody, 50ul Custom Peptide Synthesis which is thought to act

SKU: 35573142882

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LRC3B Rabbit Polyclonal Antibody, 50ul Custom Peptide Synthesis which is thought to actThe protein encoded by this gene is a tumor suppressor with lowered expression levels found in gastric renal colorectal lung and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene.

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Description

which is thought to act as a protein-ruler

The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites| implicating a role in determining and stabilizing dentritic shape during neuron development

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome

which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade

This gene functions as a tumor suppressor gene in a number of common cancers

LRC3B Rabbit Polyclonal Antibody, 50ul Custom Peptide Synthesis which is thought to actThe protein encoded by this gene is a tumor suppressor with lowered expression levels found in gastric renal colorectal lung and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene.

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