WSB2 Rabbit Polyclonal Antibody, 50ul Stepper Deletions of portions of the

Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia

KIF4A encodes a member of the kinesin 4 subfamily of kinesin related proteins

Mutations in this gene are associated with snowflake vitreoretinal degeneration

such as B cell activation

and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs

WSB2 Rabbit Polyclonal Antibody, 50ul Stepper Deletions of portions of theThis gene encodes a member of the WD protein subfamily. The encoded protein contains five WD repeats spanning most of the protein and an SOCS box in the C terminus. The SOCS box may act as a bridge between specific substrate binding domains and E3 ubiquitin protein ligases. Three transcript variants encoding different isoforms have been found for this gene.