JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates The protein localizes to membrane

The protein localizes to membrane protrusions and is often expressed on adult stem cells

Involved in the recruitment of beta-arrestin 2 ARRB2 at the plasma membrane in epithelial cells

this protein is reported to associate with centrosomes in a microtubule-dependent manner

it lacks domain VI

The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain

JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates The protein localizes to membraneThe protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).