Human Fibrous Sheath Interacting Protein 1, FSIP1 ELISA Kit, 96T Culture Tubes Component of SUN-protein-containing multivariate complexes

Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments

The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination

P-TEFb is also involved in cotranscriptional histone modification

Induces leptin production in adipocytes and reduces LRP2-mediated leptin clearance in the kidney

When overexpressed in mammalian cells

Human Fibrous Sheath Interacting Protein 1, FSIP1 ELISA Kit, 96T Culture Tubes Component of SUN-protein-containing multivariate complexes