Rock-1 Polyclonal Antibody, 50ul[BT-AP13880] Purification Defects in this gene are

Defects in this gene are a cause of polycystic kidney disease (PKD)

Mutations in this gene are associated with visceral heterotaxy-6

Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3

It has now been found that this gene is involved in the regulation of many NR and non-NR activities

The protein encoded by LAIR2 is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation

Rock-1 Polyclonal Antibody, 50ul[BT-AP13880] Purification Defects in this gene areThis gene encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response