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SPP2A Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Component of the core-TFIIH basal

SKU: 35911285125

4.5
PLN185.00 PLN230.00

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SPP2A Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Component of the core-TFIIH basalThis gene encodes a member of the GXGD family of aspartic proteases which are transmembrane proteins with two conserved catalytic motifs localized within the membrane spanning regions as well as a member of the signal peptide peptidase like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15.

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Description

Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and

This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN

An important paralog of this gene is MID1

Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding

Diseases associated with RGAG1 include non-syndromic x-linked intellectual disability

SPP2A Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation Component of the core-TFIIH basalThis gene encodes a member of the GXGD family of aspartic proteases which are transmembrane proteins with two conserved catalytic motifs localized within the membrane spanning regions as well as a member of the signal peptide peptidase like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15.

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