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LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences Cyclin dependent kinase 11B encoded

SKU: 3606051335

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DKK123.75 DKK147.75

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LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences Cyclin dependent kinase 11B encodedSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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Description

Cyclin dependent kinase 11B encoded by CDK11B can be cleaved by caspases and may play a role in cell apoptosis

This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells

GO annotations related to this gene include poly(A) RNA binding and tRNA binding

but appear to have divergent biological functions

This protein may also function in the DNA damage response

LKB1 Polyclonal Antibody, 100ul[BT-AP05039] Molecular Sciences Cyclin dependent kinase 11B encodedSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been

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