DNA pol Gamma2 Polyclonal Antibody, 20ul Measuring Instruments Mutations in BUB1 have been

Mutations in BUB1 have been associated with aneuploidy and several forms of cancer

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leading to cell cycle arrest in G1

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DNA pol Gamma2 Polyclonal Antibody, 20ul Measuring Instruments Mutations in BUB1 have beenPOLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The DNA polymerase gamma 2, accessory subunit forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.