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Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments inhibiting oncogenic beta-catenin-mediated transcriptional activation

SKU: 36305010183

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Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments inhibiting oncogenic beta-catenin-mediated transcriptional activationThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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Description

inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin

This gene encodes a protein that phosphorylates carbohydrates such as ribulose

Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression| and the zinc-fingers comprise the DNA binding domain

Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK)

The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors

Paxillin(Phospho Tyr118) Polyclonal Antibody, 20ul Measuring Instruments inhibiting oncogenic beta-catenin-mediated transcriptional activationThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).

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