RPH3L Rabbit Polyclonal Antibody, 20ul Bio-Reaction Tube Mutations in this gene cause

Mutations in this gene cause ovarian dysgenesis type 1

This subunit also shares identity with a subunit constituting the transcription factor E4TF1

including eotaxin (CCL11)

The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia

can unbiquitinate and induce the degradation of this protein

RPH3L Rabbit Polyclonal Antibody, 20ul Bio-Reaction Tube Mutations in this gene causeThe protein encoded by this gene plays a direct regulatory role in calcium ion dependent exocytosis in both endocrine and exocrine cells and plays a key role in insulin secretion by pancreatic cells. This gene is likely a tumor suppressor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.