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Ref-1 Polyclonal Antibody, 100ul[BT-AP07734] Modified Oligos Alternative splicing results in multiple

SKU: 36438152368

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Ref-1 Polyclonal Antibody, 100ul[BT-AP07734] Modified Oligos Alternative splicing results in multipleApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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Description

Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing

The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database

probably by mediating phosphorylation of dishevelled proteins (DVL1

as represented in GeneID: 106780802

The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene

Ref-1 Polyclonal Antibody, 100ul[BT-AP07734] Modified Oligos Alternative splicing results in multipleApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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