GGT2 Rabbit Polyclonal Antibody, 50ul RNA Tools Upregulated expression of this gene

Upregulated expression of this gene in astroglial cells upon exposure to lipopolysaccharides suggests a function for the encoded protein in the brain

a less severe immunodeficiency disorder

It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex| and can induce apoptosis and weakly activate the NF-kappaB transcription factor

This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells

Mutations in PLCG2 have been found in autoinflammation

GGT2 Rabbit Polyclonal Antibody, 50ul RNA Tools Upregulated expression of this geneGGT2 belongs to the gamma glutamyltransferase (GGT; EC 2. 3. 2. 2) gene family. GGT is a membrane bound extracellular enzyme that cleaves gamma glutamyl peptide bonds in glutathione and other peptides and transfers the gamma glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al. 2008