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Scn4b Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) plays a role in innate

SKU: 36521645091

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SEK162.00 SEK203.00

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Scn4b Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) plays a role in innateSodium channel subunit beta 4 encoded by SCN4B is one of several sodium channel beta subunits. These subunits interact with voltage gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein coding and one non coding transcript variant have been found for this gene.

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Description

plays a role in innate immunity and inflammation

Four alternatively spliced transcript variants encoding distinct isoforms have been described

which recruit and activate leukocytes

MIM 163729)| and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures| thereby attenuating ENOS-dependent NO production

The other predicted transmembrane region is probably a hairpin-type region embedded into the membrane

Scn4b Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) plays a role in innateSodium channel subunit beta 4 encoded by SCN4B is one of several sodium channel beta subunits. These subunits interact with voltage gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein coding and one non coding transcript variant have been found for this gene.

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