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HNF-4 Alpha/Gamma Polyclonal Antibody, 100ul[BT-AP04161] Miscellaneous Chromosomal translocations between this gene

SKU: 36547078022

4.7
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HNF-4 Alpha/Gamma Polyclonal Antibody, 100ul[BT-AP04161] Miscellaneous Chromosomal translocations between this geneHepatocyte nuclear factor 4 alpha encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal

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Description

Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis

87 or 101 kD

The encoded protein is also involved in MAP/ERK signaling pathway in specific cell types

The TGF-beta receptor type-1 is a serine/threonine protein kinase

excellent sealing performance

HNF-4 Alpha/Gamma Polyclonal Antibody, 100ul[BT-AP04161] Miscellaneous Chromosomal translocations between this geneHepatocyte nuclear factor 4 alpha encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal

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