NCF1C Rabbit Polyclonal Antibody, 20ul Drying & Desiccation Heterodimer of p45 NF-E2 and

Heterodimer of p45 NF-E2 and p18 NF-E2

Several alternatively spliced transcript variants| some of which encode distinct isoforms| have been identified

TOP2A encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

Two transcript variants encoding different isoforms have been described for this gene

The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia

NCF1C Rabbit Polyclonal Antibody, 20ul Drying & Desiccation Heterodimer of p45 NF-E2 andThe neutrophil cytosolic factor 1 (NCF1) gene encodes the 47 kDa cytosolic subunit of neutrophil NADPH oxidase which produces superoxide anion. The NCF1 gene is located in close proximity to two highly similar multi exon pseudogenes at chromosome 7q11. 23 corresponding to this gene record and GeneID: 654816. The two pseudogenes contain a dinucleotide deletion (delta GT) in exon 2 that results in a frameshift and truncation of the open reading frame