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LOXL3 Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction The protein encoded by this

SKU: 36669826093

4.2
PLN97.20 PLN144.20

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LOXL3 Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction The protein encoded by thisThis gene encodes a lysyl oxidase which likely functions as an amine oxidase and plays a role in the formation of crosslinks in collagens and elastin. Deletion of the related gene in mouse causes neonatal mortality with cleft palate spine deformity and defects in collagen organization. A mutation in this gene was found in a family with Stickler syndrome.

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Description

The protein encoded by this gene belongs to the family of G-protein coupled receptors

Through its death domain| the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein| which is known to mediate signal transduction of tumor necrosis factor receptors

This gene is a member of the inhibitor of apoptosis (IAP) gene family

Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome

Among its related pathways are LKB1 signaling events

LOXL3 Rabbit Polyclonal Antibody, 20ul sgRNA Library Construction The protein encoded by thisThis gene encodes a lysyl oxidase which likely functions as an amine oxidase and plays a role in the formation of crosslinks in collagens and elastin. Deletion of the related gene in mouse causes neonatal mortality with cleft palate spine deformity and defects in collagen organization. A mutation in this gene was found in a family with Stickler syndrome.

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