Histone H2A.Z Polyclonal Antibody, 50ul[BT-AP04008] Cellular Function Assays Homotetramers consisting of a proteolytically

Homotetramers consisting of a proteolytically cleaved form of the protein| or type A subunit| exhibit low affinity for heparin and do not interact with the ECM

This gene is a member of the regulatory factor X gene family| which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain

and tumor metastasis

Amplification and overexpression of this gene have been observed in several types of human carcinomas

The protein encoded by this gene belongs to the DMRT gene family| sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C

Histone H2A.Z Polyclonal Antibody, 50ul[BT-AP04008] Cellular Function Assays Homotetramers consisting of a proteolyticallyHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.