RAIN Polyclonal Antibody, 100ul Insect Expression Multiple chromosomal translocations involving this

Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias

Downregulation of expression of this gene by promoter hypermethylation has been observed in a wide spectrum of human malignancies

forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes

colon and lung

this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance

RAIN Polyclonal Antibody, 100ul Insect Expression Multiple chromosomal translocations involving thisMay act as effector for Golgi bound HRAS and other Ras like proteins. May promote HRAS mediated transformation.,Contains 1 dilute domain.,Contains 1 Ras associating domain.,subcellular location: Associated with perinuclear vesicles. Is recruited to Golgi stacks by activated HRAS.,subunit: Interacts with Ras family members that have been activated by GTP binding. Interacts with HRAS, RAP1A, RAP2, RRAS, RAF1 and RRAS2.,tissue specificity: Highly