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IKK Gamma Polyclonal Antibody, 50ul[BT-AP04426] Site-directed Mutagenesis Contains 2 RING-type zinc fingers

SKU: 37028666266

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IKK Gamma Polyclonal Antibody, 50ul[BT-AP04426] Site-directed Mutagenesis Contains 2 RING-type zinc fingersIKBKG encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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Description

Contains 2 RING-type zinc fingers

As with many proteins

Mutations in this gene cause platelet glycoprotein deficiency

These products include the cardiac natriuretic peptides CNP-53

tissue specificity:Overexpressed in psoriasis

IKK Gamma Polyclonal Antibody, 50ul[BT-AP04426] Site-directed Mutagenesis Contains 2 RING-type zinc fingersIKBKG encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

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