CACNA1C Rabbit Polyclonal Antibody, 100ul PCR Series encoding distinct isoforms

encoding distinct isoforms

and negatively regulate NTR induced cell death and NF-kappa B activation

Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence

4 leucine-rich repeats (LRRs)

and acts as a positive regulator of p53/TP53 stability

CACNA1C Rabbit Polyclonal Antibody, 100ul PCR Series encoding distinct isoformsThis gene encodes an alpha 1 subunit of a voltage dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha 1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha 1 alpha 2 delta beta and gamma subunits in a 1: 1: 1: 1 ratio. There are multiple isoforms of each of these proteins