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CEP63 Polyclonal Antibody, 50ul Capsule Filter the protein is an active

SKU: 37176938336

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CEP63 Polyclonal Antibody, 50ul Capsule Filter the protein is an activeThis gene encodes a protein with six coiled coil domains. The protein is localized to the centrosome, a non membraneous organelle that functions as the major microtubule organizing center in animal cells. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.

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Description

the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult

leukemias and lymphomas

and two C-terminal protein interaction domains

The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles

It occurs in plasma as two main isoforms| apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver

CEP63 Polyclonal Antibody, 50ul Capsule Filter the protein is an activeThis gene encodes a protein with six coiled coil domains. The protein is localized to the centrosome, a non membraneous organelle that functions as the major microtubule organizing center in animal cells. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.

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