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GHR Polyclonal Antibody, 100ul Cell Culture Dishes The transmembrane protein encoded by

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GHR Polyclonal Antibody, 100ul Cell Culture Dishes The transmembrane protein encoded byGHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.

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Description

The transmembrane protein encoded by this gene is a member of a family of calcium-activated chloride channels

TGFB2 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation

It is expressed only in brain and ovary

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate

GHR Polyclonal Antibody, 100ul Cell Culture Dishes The transmembrane protein encoded byGHR encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature.

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