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Trk B Polyclonal Antibody, 50ul[BT-AP09214] Enzyme Activity Assays The encoded protein forms dimers

SKU: 37414341970

4.7
SEK162.00 SEK202.00

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Trk B Polyclonal Antibody, 50ul[BT-AP09214] Enzyme Activity Assays The encoded protein forms dimersNTRK2 encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in NTRK2 have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

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Description

The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion

KDR/Flk-1 and Flt-4 are members of the class III subfamily of RTKs containing seven immunoglobulin-like repeats in their extracellular domains

The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins)

induction:Not induced by IR

cytoplasmic dynein

Trk B Polyclonal Antibody, 50ul[BT-AP09214] Enzyme Activity Assays The encoded protein forms dimersNTRK2 encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in NTRK2 have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

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