ErbB-3(Phospho Tyr1222) Polyclonal Antibody, 20ul Monoclonal Antibodies enzyme regulation:GAP activity stimulated by

enzyme regulation:GAP activity stimulated by phosphatidylinositol 4|5-bisphosphate (PIP2) and phosphatidic acid

Members of this family have three conserved domains: an N-terminal homology domain

Mutations in this gene cause primary bile acid malabsorption (PBAM)

A related pseudogene has been identified on chromosome 10

mis-segregation of sister chromatids

ErbB-3(Phospho Tyr1222) Polyclonal Antibody, 20ul Monoclonal Antibodies enzyme regulation:GAP activity stimulated byThis gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the