Raf-1 Polyclonal Antibody, 20ul[BT-AP13532] Cell Culture Dishes This gene encodes a GTP-binding

This gene encodes a GTP-binding protein that is a core component of the intraflagellar transport complex B

Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis

There are two transcripts identified for this gene

FXYD4| originally named CHIF for channel-inducing factor| has been shown to modulate the properties of the Na|K-ATPase| as has FXYD2| also known as the gamma subunit of the Na|K-ATPase| and FXYD7

Its proper function is essential for cell viability and normal NPC function

Raf-1 Polyclonal Antibody, 20ul[BT-AP13532] Cell Culture Dishes This gene encodes a GTP-bindingThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.