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EpoR Polyclonal Antibody, 50ul[BT-AP03024] Culture Plate Inserts E2F transcription factor 4 encoded

SKU: 37808052415

4.4
USD162.00 USD190.00

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EpoR Polyclonal Antibody, 50ul[BT-AP03024] Culture Plate Inserts E2F transcription factor 4 encodedEPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce

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Description

E2F transcription factor 4 encoded by E2F4 is a member of the E2F family of transcription factors

suggesting that it may play a role in Alzheimer's disease

Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration

Binds to transcription factors via its WW domain

and a MAM domain| which is believed to have an adhesive function

EpoR Polyclonal Antibody, 50ul[BT-AP03024] Culture Plate Inserts E2F transcription factor 4 encodedEPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce

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