CD59 Polyclonal Antibody, 50ul[BT-AP01987] Adenovirus Packaging Diseases associated with PRAF2 include

Diseases associated with PRAF2 include neuroblastoma

and different kinds of catalytic activities

Glycine-rich region (GRR) appears to be a critical element in the generation of p50

Additional splice variants have also been reported

The protein encoded by this gene belongs to the calreticulin family

CD59 Polyclonal Antibody, 50ul[BT-AP01987] Adenovirus Packaging Diseases associated with PRAF2 includeCLN5 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.