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LRP3 Polyclonal Antibody, 100ul Buffer Solutions Surfeit locus protein 1 is

SKU: 38127586316

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LRP3 Polyclonal Antibody, 100ul Buffer Solutions Surfeit locus protein 1 isNLRP3, also known as NALP3, CIAS1, PYPAF or Cryopyrin, is a cytosolic ~120 kDa member of the NLRP family of proteins expressed in leukocytes, especially neutrophils. As a component of the inflammasome, NLRP3 activates caspases 1 and 5. Defects in NLRP3 may cause FCAS1, CINCA, or Muckle Wells autoinflammatory syndromes. Mouse NLRP3 contains an N terminal Pyrin domain (aa 1 91) followed by a Nacht region (aa 216 532), and seven LRRs (aa 739 988). Within

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Description

Surfeit locus protein 1 is a member of the SURF1 family

metallo-endopeptidase) encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen

This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA

Sodium-dependent phosphate transport protein 2B encoded by SLC34A2 is a pH-sensitive sodium-dependent phosphate transporter

Studies in mouse show that this gene product functions as a transcription factor

LRP3 Polyclonal Antibody, 100ul Buffer Solutions Surfeit locus protein 1 isNLRP3, also known as NALP3, CIAS1, PYPAF or Cryopyrin, is a cytosolic ~120 kDa member of the NLRP family of proteins expressed in leukocytes, especially neutrophils. As a component of the inflammasome, NLRP3 activates caspases 1 and 5. Defects in NLRP3 may cause FCAS1, CINCA, or Muckle Wells autoinflammatory syndromes. Mouse NLRP3 contains an N terminal Pyrin domain (aa 1 91) followed by a Nacht region (aa 216 532), and seven LRRs (aa 739 988). Within

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