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Nup88 Polyclonal Antibody, 100ul Microbial Genome Editing It interacts with POLR2A

SKU: 38144411330

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Nup88 Polyclonal Antibody, 100ul Microbial Genome Editing It interacts with POLR2AThe nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. Nuclear pore complex protein Nup88 encoded by NUP88 belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN Nup214

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Description

It interacts with POLR2A

and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system

The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins

Gene copy number variations in the human chromosomal region 1q21

Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure

Nup88 Polyclonal Antibody, 100ul Microbial Genome Editing It interacts with POLR2AThe nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. Nuclear pore complex protein Nup88 encoded by NUP88 belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN Nup214

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