p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11716] Sampling Tubes SFTPB encodes the pulmonary-associated surfactant

SFTPB encodes the pulmonary-associated surfactant protein B (SPB)

and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD)

This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation

upon B cell activation

In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM

p53 Rabbit Polyclonal Antibody, 100ul[BT-AP11716] Sampling Tubes SFTPB encodes the pulmonary-associated surfactantThis gene encodes a tumor suppressor protein containing transcriptional activation DNA binding and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes thereby inducing cell cycle arrest apoptosis senescence DNA repair or changes in metabolism. Mutations in this gene are associated with a variety of human cancers including hereditary cancers such as Li Fraumeni syndrome. Alternative