Histone H2B(Phospho-Ser14) Rabbit Polyclonal Antibody, 20ul Centrifugal Filter The tumor suppressor function of

The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and acidic nuclear phosphoprotein 32 family member C encoded by ANP32C

The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage

where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene

Receptor protein tyrosine kinases

Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis

Histone H2B(Phospho-Ser14) Rabbit Polyclonal Antibody, 20ul Centrifugal Filter The tumor suppressor function ofHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A H2B H3 and H4) form an octamer around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene