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FA11 Rabbit Polyclonal Antibody, 100ul[BT-AP09939] Centrifugal Filter The encoded protein (Cbl proto-oncogene)

SKU: 38272787613

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PLN141.00 PLN190.00

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FA11 Rabbit Polyclonal Antibody, 100ul[BT-AP09939] Centrifugal Filter The encoded protein (Cbl proto-oncogene)This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains resulting in activated factor XIa a serine protease

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Description

The encoded protein (Cbl proto-oncogene) is one of the enzymes required for targeting substrates for degradation by the proteasome

APC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway

The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al

The upstream stimulatory factor 2 can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs and is involved in regulating multiple cellular processes

RFC3 encodes the 38 kDa subunit

FA11 Rabbit Polyclonal Antibody, 100ul[BT-AP09939] Centrifugal Filter The encoded protein (Cbl proto-oncogene)This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains resulting in activated factor XIa a serine protease

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