MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath ZADH2 (zinc binding alcohol dehydrogenase

ZADH2 (zinc binding alcohol dehydrogenase domain containing 2) is a 377 amino acid protein that belongs to the zinc-containing alcohol dehydrogenase family and is encoded by a gene which maps to human chromosome 18

This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics

including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis

tongue and small intestine and in endocrine glands such as thyroid and adrenal gland

It is expressed in the tissue and circulating myeloid leukocytes

MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath ZADH2 (zinc binding alcohol dehydrogenaseThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript