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MFAP5 Polyclonal Antibody, 50ul Primary Antibodies The encoded protein regulates endoplasmic

SKU: 38316374718

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MFAP5 Polyclonal Antibody, 50ul Primary Antibodies The encoded protein regulates endoplasmicThis gene encodes a 25 kD microfibril associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha V beta 3 integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms.

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Description

The encoded protein regulates endoplasmic reticulum to Golgi transport and plays a critical role in autophagy

consistent with the observation that it binds directly to pre-mRNA

There is a related gene located adjacent to this gene on chromosome 21

This protein (apoptotic peptidase activating factor 1) contains several copies of the WD-40 domain

An important paralog of this gene is SPRED1

MFAP5 Polyclonal Antibody, 50ul Primary Antibodies The encoded protein regulates endoplasmicThis gene encodes a 25 kD microfibril associated glycoprotein which is a component of microfibrils of the extracellular matrix. The encoded protein promotes attachment of cells to microfibrils via alpha V beta 3 integrin. Deficiency of this gene in mice results in neutropenia. Alternate splicing results in multiple transcript variants encoding different isoforms.

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