Cytokeratin (Pan) Monoclonal Antibody, 50ul[BT-MCA0418] Reagent Reservoirs It also displays neuroprotective effects

It also displays neuroprotective effects in animal models

The protein encoded by PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis

Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways

The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress

The protein consists of a tetramer of identical subunits

Cytokeratin (Pan) Monoclonal Antibody, 50ul[BT-MCA0418] Reagent Reservoirs It also displays neuroprotective effectsThe protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of