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CD232 Polyclonal Antibody, 20ul Pathway and Network Analysis Mutations in this gene cause

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CD232 Polyclonal Antibody, 20ul Pathway and Network Analysis Mutations in this gene causePLXNC1 encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The plexin C1 and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript

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Description

Mutations in this gene cause CD59 deficiency

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The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration

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CD232 Polyclonal Antibody, 20ul Pathway and Network Analysis Mutations in this gene causePLXNC1 encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The plexin C1 and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript

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