Human Grb2-associated-binding Protein 2, GAB2 ELISA Kit, 96T Plasma Several transcript variants encoding different

Several transcript variants encoding different isoforms| have been identified for this gene

L-tryptophan

Studies have also characterized the protein as an RNA polymerase II elongation factor

Promotes apoptosis by favouring the activation of caspase-9/CASP9 and allowing apoptosome formation (PubMed: 18439902)

which translocates to the nucleus to function as a transcription factor

Human Grb2-associated-binding Protein 2, GAB2 ELISA Kit, 96T Plasma Several transcript variants encoding differentAdapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI 3 kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.