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Collagen XI alpha 1 Polyclonal Antibody, 50ul Nucleic Acid Amplification The protein encoded by this

SKU: 38588436294

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Collagen XI alpha 1 Polyclonal Antibody, 50ul Nucleic Acid Amplification The protein encoded by thisThis gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants

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Description

The protein encoded by this gene enhances transcriptional activation by ligand-bound nuclear hormone receptors

The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation

Unlike other proteins of the group| which cycle in the early secretory pathway and are predominantly associated with post endoplasmic reticulum membranes| the protein encoded by this gene is a non-cycling resident protein of the ER| where it functions as a cargo receptor for glycoproteins

temperature and time

Alternatively spliced transcript variants have been found for CSE1L

Collagen XI alpha 1 Polyclonal Antibody, 50ul Nucleic Acid Amplification The protein encoded by thisThis gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants

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