PON1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges The RING finger and B-box

The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions

one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver

Four capacities: 4 mL

Mutations in this gene are associated with hypochromic microcytic anemia with iron overload

tissue specificity:Expressed by nucleated hematopoietic cells (at protein level)

PON1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges The RING finger and B-boxThe enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21. 3.