CD110 Polyclonal Antibody, 50ul[BT-AP01341] Endonucleases & Exonucleases CYP26A1 encodes a member of

CYP26A1 encodes a member of the cytochrome P450 superfamily of enzymes

TLR9 and TRAF6

TOP2A encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

Represses the ligand-dependent transcriptional activation function of ESR2 (PubMed: 20074560)

Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex

CD110 Polyclonal Antibody, 50ul[BT-AP01341] Endonucleases & Exonucleases CYP26A1 encodes a member ofIn 1990 an oncogene, v mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c mpl, was cloned. Sequence data revealed that c mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti sense oligodeoxynucleotides of c mpl inhibited megakaryocyte colony