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Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection

5mL adapter

Mutations in this gene cause Diamond-Blackfan anemia 4

In response to TGF-beta signal

Peroxin 2 Polyclonal Antibody, 100ul Multiplex Immunoassays Conquer scientific challenges and takePEX2 encodes an integral peroxisomal membrane protein required for peroxisome biogenesis. Peroxisomal biogenesis factor 2 is thought to be involved in peroxisomal matrix protein import. Mutations in PEX2 result in one form of Zellweger syndrome and infantile Refsum disease. Alternative splicing results in multiple transcript variants encoding the same protein.