Human Carboxypeptidase A4, CPA4 ELISA Kit, 96T Virus Packaging The protein encoded by MRC1

The protein encoded by MRC1 is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages

tissue specificity:Expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils)

Once activated by a ligand

The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6| and may also regulate zinc sequestration into secretory granules of pancreatic beta cells

Appears to function as signaling scaffold involved in regulation of MIP-1-beta-stimulated CCR5-dependent chemotaxis

Human Carboxypeptidase A4, CPA4 ELISA Kit, 96T Virus Packaging The protein encoded by MRC1